Drug interactions
Etanercept + Measles vaccine
Severity: Contraindicated
Etanercept and Measles vaccine: contraindicated interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Measles vaccine is live attenuated, and TNF blockade may allow uncontrolled vaccine virus replication. Disseminated vaccine-strain infection is a theoretical risk. Immune response may also be reduced.
What this interaction means in plain words
Etanercept and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Why it happens
Immunosuppression from TNF inhibition reduces control of live attenuated virus replication.
What to do
Avoid live measles vaccine during etanercept therapy. Vaccinate at least 4 weeks before starting treatment where possible, or after an adequate washout, and consider immunoglobulin if exposed.
What to ask your pharmacist
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Other interactions of Etanercept
- Bcg vaccine live + Etanercept Contraindicated
- Etanercept + Golimumab Contraindicated
- Etanercept + Measles mumps and rubella vaccine Contraindicated
- Etanercept + Measles mumps and rubella vaccine live Contraindicated
- Etanercept + Measles mumps rubella and varicella vaccine live Contraindicated
- Etanercept + Rubella vaccine Contraindicated
Frequently asked questions
Can I take Etanercept with Measles vaccine?
MediHelp rates the interaction as contraindicated. Etanercept and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and TNF blockade may allow uncontrolled vaccine virus replication. Disseminated vaccine-strain infection is a theoretical risk. Immune response may also be reduced.
How serious is the interaction between Etanercept and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live measles vaccine during etanercept therapy. Vaccinate at least 4 weeks before starting treatment where possible, or after an adequate washout, and consider immunoglobulin if exposed.
What other medicines interact with Etanercept?
MediHelp also lists interactions of Etanercept with, for example, Bcg vaccine live, Golimumab, Measles mumps and rubella vaccine. The full list is on the Etanercept page.
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