Drug reference
etanercept
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Musculoskeletal (TNF-alpha Inhibitors)
Mechanism of action
Binds and inactivates TNF (Tumor necrosis factor alpha) which is a pro-inflammatory cytokine produced by macrophages and lymphocytes. It is found in large quantities in rheumatoid joint., thereby preventing synovial inflammation
Common side effects
- Injection site reactions
- Pruritus
- Urticaria
- Upper respiratory infections
- Aplastic anemia
- Diarrhea
Contraindications
- Sepsis Hypersensitivity
Known interactions (5)
- etanercept + measles mumps and rubella vaccine Contraindicated
- abatacept + etanercept Major
- etanercept + upadacitinib Major
- etanercept + hepatitis a vaccine inactivated Moderate
- etanercept + pneumococcal vaccine 13-valent Moderate
Related conditions
Frequently asked questions
What drug class is etanercept?
etanercept belongs to: Musculoskeletal.
How does etanercept work?
Binds and inactivates TNF (Tumor necrosis factor alpha) which is a pro-inflammatory cytokine produced by macrophages and lymphocytes. It is found in large quantities in rheumatoid joint., thereby preventing synovial inflammation
What are the common side effects of etanercept?
Injection site reactions, Pruritus, Urticaria, Upper respiratory infections, Aplastic anemia, Diarrhea
Which drugs interact with etanercept?
measles mumps and rubella vaccine, abatacept, upadacitinib, hepatitis a vaccine inactivated, pneumococcal vaccine 13-valent
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