Drug interactions
Ethanol + Haloperidol
Severity: Moderate
Ethanol and Haloperidol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol and haloperidol both depress the CNS, causing greater drowsiness, impaired coordination and judgment, and possible hypotension. Alcohol may also worsen extrapyramidal side effects and impair adherence.
What this interaction means in plain words
Ethanol and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Advise patients to avoid alcohol during haloperidol therapy and warn about driving and machinery.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Ethanol and Haloperidol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Haloperidol
- Dofetilide + Haloperidol Contraindicated
- Dronedarone + Haloperidol Contraindicated
- Haloperidol + Ibutilide Contraindicated
- Haloperidol + Levoketoconazole Contraindicated
- Haloperidol + Panobinostat Contraindicated
- Haloperidol + Pimozide Contraindicated
Frequently asked questions
Can I take Ethanol with Haloperidol?
MediHelp rates the interaction as moderate. Ethanol and Haloperidol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol and haloperidol both depress the CNS, causing greater drowsiness, impaired coordination and judgment, and possible hypotension. Alcohol may also worsen extrapyramidal side effects and impair adherence.
How serious is the interaction between Ethanol and Haloperidol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid alcohol during haloperidol therapy and warn about driving and machinery.
What other medicines interact with Haloperidol?
MediHelp also lists interactions of Haloperidol with, for example, Dofetilide, Dronedarone, Ibutilide. The full list is on the Haloperidol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
