Drug interactions
Ethinyl estradiol-drospirenone + Formoterol
Severity: Minor
Ethinyl estradiol-drospirenone and Formoterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Drospirenone can raise potassium, whereas formoterol, a beta-2 agonist, drives potassium into cells and can lower serum levels. The opposing effects make the net change small and unpredictable.
What this interaction means in plain words
Ethinyl estradiol-drospirenone and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ethinyl estradiol-drospirenone belongs to Endocrine; Formoterol belongs to Respiratory.
Why it happens
Opposing effects on potassium: aldosterone antagonism by drospirenone versus beta-2-mediated cellular potassium uptake from formoterol.
What to do
No routine action is needed with standard inhaled doses. Check serum potassium if high doses are used or the patient has renal disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-drospirenone Major
- Amobarbital + Ethinyl estradiol-drospirenone Major
Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Frequently asked questions
Can I take Ethinyl estradiol-drospirenone with Formoterol?
MediHelp rates the interaction as minor. Ethinyl estradiol-drospirenone and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Drospirenone can raise potassium, whereas formoterol, a beta-2 agonist, drives potassium into cells and can lower serum levels. The opposing effects make the net change small and unpredictable.
How serious is the interaction between Ethinyl estradiol-drospirenone and Formoterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed with standard inhaled doses. Check serum potassium if high doses are used or the patient has renal disease.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
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