Drug reference
ethinyl estradiol-drospirenone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Gonadal Hormones)
Mechanism of action
Ethinyl estradiol: Reduces LHRH release from hypothalamus, reduces gonadotropin release from pituitary; increases synthesis of DNA, RNA, and various proteins in target tissues; Drospirenone: Progestin; spironolactone analogue with anti-mineralocorticoid and anti-androgenic activity
Common side effects
- Vomiting
- Nausea
- Premenstrual syndrome
- Migraine
- Breast pain/discomfort/tenderness
- Menstrual irregularities
- Abdominal pain/discomfort/tenderness
Known interactions (6)
- enoxaparin + ethinyl estradiol-drospirenone Major
- eplerenone + ethinyl estradiol-drospirenone Major
- ethinyl estradiol-drospirenone + heparin Major
- amiloride + ethinyl estradiol-drospirenone Moderate
- ethinyl estradiol-drospirenone + spironolactone Moderate
- ethinyl estradiol-drospirenone + triamterene Moderate
Related conditions
Frequently asked questions
What drug class is ethinyl estradiol-drospirenone?
ethinyl estradiol-drospirenone belongs to: Endocrine.
How does ethinyl estradiol-drospirenone work?
Ethinyl estradiol: Reduces LHRH release from hypothalamus, reduces gonadotropin release from pituitary; increases synthesis of DNA, RNA, and various proteins in target tissues; Drospirenone: Progestin; spironolactone analogue with anti-mineralocorticoid and anti-androgenic activity
What are the common side effects of ethinyl estradiol-drospirenone?
Vomiting, Nausea, Premenstrual syndrome, Migraine, Breast pain/discomfort/tenderness, Menstrual irregularities, Abdominal pain/discomfort/tenderness
Which drugs interact with ethinyl estradiol-drospirenone?
enoxaparin, eplerenone, heparin, amiloride, spironolactone, triamterene
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