Drug interactions
Ethinyl estradiol-drospirenone + Metaproterenol
Severity: Minor
Ethinyl estradiol-drospirenone and Metaproterenol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Drospirenone tends to raise potassium whereas metaproterenol, a beta-agonist, can lower serum potassium through intracellular shift. The effects are partly opposite and a significant clinical interaction is not expected at usual doses.
What this interaction means in plain words
Ethinyl estradiol-drospirenone and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing effects on serum potassium: drospirenone antimineralocorticoid action versus beta-agonist driven cellular uptake.
What to do
No routine action is needed. Check potassium if high doses of metaproterenol are used or other risk factors for potassium disturbance are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-drospirenone Major
- Amobarbital + Ethinyl estradiol-drospirenone Major
Frequently asked questions
Can I take Ethinyl estradiol-drospirenone with Metaproterenol?
MediHelp rates the interaction as minor. Ethinyl estradiol-drospirenone and Metaproterenol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Drospirenone tends to raise potassium whereas metaproterenol, a beta-agonist, can lower serum potassium through intracellular shift. The effects are partly opposite and a significant clinical interaction is not expected at usual doses.
How serious is the interaction between Ethinyl estradiol-drospirenone and Metaproterenol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed. Check potassium if high doses of metaproterenol are used or other risk factors for potassium disturbance are present.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
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