Drug interactions
Ethinyl estradiol-drospirenone + Ticarcillin
Severity: Minor
Ethinyl estradiol-drospirenone and Ticarcillin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ticarcillin is given intravenously, often as a sodium salt with potassium-containing formulations in some combinations, but there is no solid evidence for a meaningful interaction with the contraceptive. Reduced contraceptive efficacy from penicillins is theoretical.
What this interaction means in plain words
Ethinyl estradiol-drospirenone and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; a gut flora effect on estrogen recycling is proposed but unproven.
What to do
No change to contraception is needed. Check potassium only if other risk factors for hyperkalemia are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ethinyl estradiol-drospirenone
- Ethinyl estradiol-drospirenone + Fezolinetant Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir Contraindicated
- Ethinyl estradiol-drospirenone + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contraindicated
- Ethinyl estradiol-drospirenone + Tranexamic acid Contraindicated
- Aminocaproic acid + Ethinyl estradiol-drospirenone Major
- Amobarbital + Ethinyl estradiol-drospirenone Major
Frequently asked questions
Can I take Ethinyl estradiol-drospirenone with Ticarcillin?
MediHelp rates the interaction as minor. Ethinyl estradiol-drospirenone and Ticarcillin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ticarcillin is given intravenously, often as a sodium salt with potassium-containing formulations in some combinations, but there is no solid evidence for a meaningful interaction with the contraceptive. Reduced contraceptive efficacy from penicillins is theoretical.
How serious is the interaction between Ethinyl estradiol-drospirenone and Ticarcillin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change to contraception is needed. Check potassium only if other risk factors for hyperkalemia are present.
What other medicines interact with Ethinyl estradiol-drospirenone?
MediHelp also lists interactions of Ethinyl estradiol-drospirenone with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir, Ombitasvir / paritaprevir / ritonavir and dasabuvir. The full list is on the Ethinyl estradiol-drospirenone page.
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