Drug interactions
Etonogestrel + Quinupristin / dalfopristin
Severity: Minor
Etonogestrel and Quinupristin / dalfopristin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinupristin/dalfopristin inhibits CYP3A4 and may modestly raise etonogestrel exposure. Clinical significance is likely small given the short courses and the wide margin of the contraceptive.
What this interaction means in plain words
Etonogestrel and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Quinupristin/dalfopristin inhibits CYP3A4, reducing etonogestrel metabolism.
What to do
No routine change is needed; be aware of possible progestogenic adverse effects during the antibiotic course.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Etonogestrel
Frequently asked questions
Can I take Etonogestrel with Quinupristin / dalfopristin?
MediHelp rates the interaction as minor. Etonogestrel and Quinupristin / dalfopristin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quinupristin/dalfopristin inhibits CYP3A4 and may modestly raise etonogestrel exposure. Clinical significance is likely small given the short courses and the wide margin of the contraceptive.
How serious is the interaction between Etonogestrel and Quinupristin / dalfopristin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; be aware of possible progestogenic adverse effects during the antibiotic course.
What other medicines interact with Etonogestrel?
MediHelp also lists interactions of Etonogestrel with, for example, Amobarbital, Armodafinil, Bosentan. The full list is on the Etonogestrel page.
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