Drug interactions
Etrasimod + Nimodipine
Severity: Minor
Etrasimod and Nimodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Etrasimod can transiently slow heart rate and AV conduction when started. Nimodipine is mainly a vasodilator, so any additive bradycardia effect is expected to be small, but it is not well studied.
What this interaction means in plain words
Etrasimod and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Etrasimod belongs to Gastrointestinal Tract; Nimodipine belongs to Cardiovascular.
Why it happens
Possible additive effects on heart rate and conduction; nimodipine has little direct nodal effect.
What to do
Monitor heart rate and blood pressure when starting etrasimod. Take extra care if other rate-lowering drugs are also being used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Other interactions of Etrasimod
- Abatacept + Etrasimod Major
- Amiodarone + Etrasimod Major
- Anagrelide + Etrasimod Major
- Anakinra + Etrasimod Major
- Anti-thymocyte + Etrasimod Major
- Asenapine + Etrasimod Major
Frequently asked questions
Can I take Etrasimod with Nimodipine?
MediHelp rates the interaction as minor. Etrasimod and Nimodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Etrasimod can transiently slow heart rate and AV conduction when started. Nimodipine is mainly a vasodilator, so any additive bradycardia effect is expected to be small, but it is not well studied.
How serious is the interaction between Etrasimod and Nimodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure when starting etrasimod. Take extra care if other rate-lowering drugs are also being used.
What other medicines interact with Nimodipine?
MediHelp also lists interactions of Nimodipine with, for example, Apalutamide, Carbamazepine, Ceritinib. The full list is on the Nimodipine page.
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