Drug interactions
Eucalyptus + Voriconazole
Severity: Minor
Eucalyptus and Voriconazole: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eucalyptus oil constituents are metabolized in part by CYP3A4, so voriconazole could raise their levels. Systemic exposure from typical herbal use is variable and clinically important effects are not well documented.
What this interaction means in plain words
Eucalyptus and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical CYP3A4 inhibition by voriconazole reducing metabolism of eucalyptus constituents.
What to do
Avoid ingesting concentrated eucalyptus oil during voriconazole therapy; routine topical or inhaled use needs no change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Eucalyptus with Voriconazole?
MediHelp rates the interaction as minor. Eucalyptus and Voriconazole have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eucalyptus oil constituents are metabolized in part by CYP3A4, so voriconazole could raise their levels. Systemic exposure from typical herbal use is variable and clinically important effects are not well documented.
How serious is the interaction between Eucalyptus and Voriconazole?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ingesting concentrated eucalyptus oil during voriconazole therapy; routine topical or inhaled use needs no change.
What other medicines interact with Voriconazole?
MediHelp also lists interactions of Voriconazole with, for example, Avanafil, Butabarbital, Carbamazepine. The full list is on the Voriconazole page.
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