Drug interactions
Exemestane + Iloperidone
Severity: Minor
Exemestane and Iloperidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iloperidone may weakly inhibit CYP3A4 and slightly raise exemestane levels. The clinical impact is expected to be small.
What this interaction means in plain words
Exemestane and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Exemestane belongs to Oncology; Iloperidone belongs to Central Nervous System.
Why it happens
Weak inhibition of CYP3A4-mediated exemestane metabolism.
What to do
No dose adjustment is needed; monitor for exemestane adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Exemestane
Other interactions of Iloperidone
- Iloperidone + Thioridazine Contraindicated
- Alfuzosin + Iloperidone Major
- Amiodarone + Iloperidone Major
- Amisulpride + Iloperidone Major
- Amitriptyline + Iloperidone Major
- Anagrelide + Iloperidone Major
Frequently asked questions
Can I take Exemestane with Iloperidone?
MediHelp rates the interaction as minor. Exemestane and Iloperidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Iloperidone may weakly inhibit CYP3A4 and slightly raise exemestane levels. The clinical impact is expected to be small.
How serious is the interaction between Exemestane and Iloperidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor for exemestane adverse effects.
What other medicines interact with Exemestane?
MediHelp also lists interactions of Exemestane with, for example, Bazedoxifene-conjugated estrogens, Desogestrel-ethinyl estradiol, Estradiol. The full list is on the Exemestane page.
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