Drug interactions
Felodipine + Terazosin
Severity: Moderate
Felodipine and Terazosin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs lower blood pressure, so together they can cause additive hypotension, dizziness and syncope, particularly when treatment is started or doses are increased.
What this interaction means in plain words
Felodipine and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Felodipine belongs to Cardiovascular; Terazosin belongs to Genitourinary.
Why it happens
Additive vasodilation from alpha-1 adrenergic blockade and dihydropyridine calcium channel blockade.
What to do
Monitor blood pressure including orthostatic readings during initiation and titration. Give the first terazosin dose at bedtime.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Terazosin?
MediHelp rates the interaction as moderate. Felodipine and Terazosin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower blood pressure, so together they can cause additive hypotension, dizziness and syncope, particularly when treatment is started or doses are increased.
How serious is the interaction between Felodipine and Terazosin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure including orthostatic readings during initiation and titration. Give the first terazosin dose at bedtime.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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