Drug interactions
Felodipine + Timolol
Severity: Minor
Felodipine and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Combining a beta-blocker with a dihydropyridine calcium channel blocker gives additive blood pressure lowering. Felodipine may cause reflex tachycardia that timolol blunts, which is often beneficial. Occasionally hypotension or, rarely, worsened heart failure can occur in susceptible patients.
What this interaction means in plain words
Felodipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Felodipine belongs to Cardiovascular; Timolol belongs to Cardiovascular.
Why it happens
Additive pharmacodynamic antihypertensive effects through beta-blockade and arterial vasodilation via calcium channel blockade.
What to do
Monitor blood pressure and heart rate when starting or adjusting either drug. Adjust doses if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Felodipine with Timolol?
MediHelp rates the interaction as minor. Felodipine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Combining a beta-blocker with a dihydropyridine calcium channel blocker gives additive blood pressure lowering. Felodipine may cause reflex tachycardia that timolol blunts, which is often beneficial. Occasionally hypotension or, rarely, worsened heart failure can occur in susceptible patients.
How serious is the interaction between Felodipine and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting either drug. Adjust doses if symptomatic hypotension occurs.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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