Drug interactions
Fenofibrate micronized + Furosemide
Severity: Minor
Fenofibrate micronized and Furosemide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs are highly protein bound, and displacement from albumin has been proposed to raise free concentrations of either drug. The clinical importance is uncertain and is most plausible in patients with low albumin, where furosemide effects or fenofibrate effects could be intensified.
What this interaction means in plain words
Fenofibrate micronized and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical competition for plasma albumin binding sites increasing unbound drug fractions.
What to do
No routine adjustment needed; in hypoalbuminemic patients monitor diuretic response, hydration and renal function, and lipid-related adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Furosemide
- Amifostine + Furosemide Major
- Amikacin + Furosemide Major
- Carbenoxolone + Furosemide Major
- Cephaloridine + Furosemide Major
- Cisplatin + Furosemide Major
- Digoxin + Furosemide Major
Frequently asked questions
Can I take Fenofibrate micronized with Furosemide?
MediHelp rates the interaction as minor. Fenofibrate micronized and Furosemide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs are highly protein bound, and displacement from albumin has been proposed to raise free concentrations of either drug. The clinical importance is uncertain and is most plausible in patients with low albumin, where furosemide effects or fenofibrate effects could be intensified.
How serious is the interaction between Fenofibrate micronized and Furosemide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment needed; in hypoalbuminemic patients monitor diuretic response, hydration and renal function, and lipid-related adverse effects.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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