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Drug interactions

Ferrous fumarate + Moxifloxacin

Severity: Moderate

Ferrous fumarate and Moxifloxacin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oral iron binds moxifloxacin in the gut and reduces its absorption, which can lower antibiotic levels and risk treatment failure. The interaction concerns oral dosing of both agents.

What this interaction means in plain words

Ferrous fumarate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ferrous fumarate belongs to Miscellaneous; Moxifloxacin belongs to Anti Bacterial.

Evidence level: High

Why it happens

Chelation of moxifloxacin by ferrous iron in the gastrointestinal tract, reducing absorption.

What to do

Give moxifloxacin at least 4 hours before or 8 hours after oral iron.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Ferrous fumarate with Moxifloxacin?

MediHelp rates the interaction as moderate. Ferrous fumarate and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron binds moxifloxacin in the gut and reduces its absorption, which can lower antibiotic levels and risk treatment failure. The interaction concerns oral dosing of both agents.

How serious is the interaction between Ferrous fumarate and Moxifloxacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give moxifloxacin at least 4 hours before or 8 hours after oral iron.

What other medicines interact with Moxifloxacin?

MediHelp also lists interactions of Moxifloxacin with, for example, Amiodarone, Arsenic trioxide, Disopyramide. The full list is on the Moxifloxacin page.

Full monographs, dosing and an interaction checker in the MediHelp app

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