Drug interactions
Ferrous fumarate + Omadacycline
Severity: Moderate
Ferrous fumarate and Omadacycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral iron forms poorly absorbed complexes with omadacycline in the gut, lowering its absorption. This can reduce antibacterial exposure and risk treatment failure.
What this interaction means in plain words
Ferrous fumarate and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous fumarate belongs to Miscellaneous; Omadacycline belongs to Anti Bacterial.
Why it happens
Chelation of omadacycline by polyvalent iron cations in the gastrointestinal tract reduces its absorption.
What to do
Give omadacycline at least 4 hours before or after oral iron products. Consider holding iron during the antibiotic course if feasible.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous fumarate
Other interactions of Omadacycline
- Acitretin + Omadacycline Contraindicated
- Isotretinoin + Omadacycline Major
- Omadacycline + Tretinoin Major
- Aluminum hydroxide + Omadacycline Moderate
- Amoxicillin-clavulanic acid + Omadacycline Moderate
- Amoxicillin + Omadacycline Moderate
Frequently asked questions
Can I take Ferrous fumarate with Omadacycline?
MediHelp rates the interaction as moderate. Ferrous fumarate and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral iron forms poorly absorbed complexes with omadacycline in the gut, lowering its absorption. This can reduce antibacterial exposure and risk treatment failure.
How serious is the interaction between Ferrous fumarate and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give omadacycline at least 4 hours before or after oral iron products. Consider holding iron during the antibiotic course if feasible.
What other medicines interact with Ferrous fumarate?
MediHelp also lists interactions of Ferrous fumarate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous fumarate page.
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