Drug interactions
Ferrous gluconate + Sarecycline
Severity: Moderate
Ferrous gluconate and Sarecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Iron can bind oral sarecycline in the gut and reduce its absorption, potentially weakening its effect on acne.
What this interaction means in plain words
Ferrous gluconate and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ferrous gluconate belongs to Miscellaneous; Sarecycline belongs to Anti Bacterial.
Why it happens
Iron cations chelate the tetracycline in the gastrointestinal tract, decreasing absorption.
What to do
Separate sarecycline and oral iron by at least 2 to 3 hours. Monitor for reduced clinical response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ferrous gluconate
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Ferrous gluconate with Sarecycline?
MediHelp rates the interaction as moderate. Ferrous gluconate and Sarecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron can bind oral sarecycline in the gut and reduce its absorption, potentially weakening its effect on acne.
How serious is the interaction between Ferrous gluconate and Sarecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate sarecycline and oral iron by at least 2 to 3 hours. Monitor for reduced clinical response.
What other medicines interact with Ferrous gluconate?
MediHelp also lists interactions of Ferrous gluconate with, for example, Ciprofloxacin, Acetohydroxamic acid, Aluminum hydroxide. The full list is on the Ferrous gluconate page.
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