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Drug interactions

Fesoterodine + Flavoxate

Severity: Moderate

Fesoterodine and Flavoxate: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Fesoterodine is an antimuscarinic for overactive bladder, so adding flavoxate duplicates anticholinergic therapy. This raises the risk of dry mouth, constipation, urinary retention and blurred vision without clear added benefit.

What this interaction means in plain words

Fesoterodine and Flavoxate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Fesoterodine belongs to Genitourinary; Flavoxate belongs to Genitourinary.

Evidence level: Moderate

Why it happens

Additive antimuscarinic pharmacodynamic effects.

What to do

Avoid combining bladder antimuscarinics unless clearly needed. If combined, monitor post-void residual volume and bowel function.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fesoterodine with Flavoxate?

MediHelp rates the interaction as moderate. Fesoterodine and Flavoxate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fesoterodine is an antimuscarinic for overactive bladder, so adding flavoxate duplicates anticholinergic therapy. This raises the risk of dry mouth, constipation, urinary retention and blurred vision without clear added benefit.

How serious is the interaction between Fesoterodine and Flavoxate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining bladder antimuscarinics unless clearly needed. If combined, monitor post-void residual volume and bowel function.

What other medicines interact with Flavoxate?

MediHelp also lists interactions of Flavoxate with, for example, Clozapine, Abobotulinumtoxina, Aclidinium. The full list is on the Flavoxate page.

Full monographs, dosing and an interaction checker in the MediHelp app

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