Drug interactions
Fesoterodine + Ipratropium-salbutamol
Severity: Minor
Fesoterodine and Ipratropium-salbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fesoterodine is a systemic antimuscarinic, and inhaled ipratropium has a similar action at muscarinic receptors. Additive anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision are possible. Because inhaled ipratropium is poorly absorbed, the effect is usually small at standard doses.
What this interaction means in plain words
Fesoterodine and Ipratropium-salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism, with limited systemic ipratropium exposure after inhalation.
What to do
No dose change is usually needed; ask about anticholinergic symptoms such as urinary retention, constipation and dry mouth. Take extra care in elderly patients or those with narrow-angle glaucoma or bladder outlet obstruction.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ipratropium-salbutamol
Other interactions of Fesoterodine
Frequently asked questions
Can I take Fesoterodine with Ipratropium-salbutamol?
MediHelp rates the interaction as minor. Fesoterodine and Ipratropium-salbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fesoterodine is a systemic antimuscarinic, and inhaled ipratropium has a similar action at muscarinic receptors. Additive anticholinergic effects such as dry mouth, constipation, urinary retention and blurred vision are possible. Because inhaled ipratropium is poorly absorbed, the effect is usually small at standard doses.
How serious is the interaction between Fesoterodine and Ipratropium-salbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; ask about anticholinergic symptoms such as urinary retention, constipation and dry mouth. Take extra care in elderly patients or those with narrow-angle glaucoma or bladder outlet obstruction.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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