Drug interactions
Fesoterodine + Pancuronium
Severity: Minor
Fesoterodine and Pancuronium: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pancuronium has vagolytic effects that add to the antimuscarinic action of fesoterodine, which may increase heart rate. The clinical effect is generally small and occurs mainly in the perioperative setting.
What this interaction means in plain words
Fesoterodine and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Pancuronium belongs to Musculoskeletal.
Why it happens
Additive muscarinic blockade; pancuronium blocks cardiac muscarinic receptors.
What to do
Monitor heart rate and rhythm during anesthesia. Consider holding fesoterodine perioperatively if tachycardia or urinary retention is a concern.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fesoterodine
Other interactions of Pancuronium
Frequently asked questions
Can I take Fesoterodine with Pancuronium?
MediHelp rates the interaction as minor. Fesoterodine and Pancuronium have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pancuronium has vagolytic effects that add to the antimuscarinic action of fesoterodine, which may increase heart rate. The clinical effect is generally small and occurs mainly in the perioperative setting.
How serious is the interaction between Fesoterodine and Pancuronium?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and rhythm during anesthesia. Consider holding fesoterodine perioperatively if tachycardia or urinary retention is a concern.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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