Drug interactions
Fesoterodine + Rimabotulinumtoxinb
Severity: Moderate
Fesoterodine and Rimabotulinumtoxinb: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Anticholinergic drugs may potentiate botulinum toxin effects, increasing neuromuscular weakness and systemic anticholinergic effects. Rimabotulinumtoxin B in particular is associated with dry mouth, which may be compounded.
What this interaction means in plain words
Fesoterodine and Rimabotulinumtoxinb can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fesoterodine belongs to Genitourinary; Rimabotulinumtoxinb belongs to Musculoskeletal.
Why it happens
Additive impairment of cholinergic neurotransmission.
What to do
Monitor for generalized weakness, dysphagia, respiratory difficulty and marked dry mouth after injection. Consider holding fesoterodine if these develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fesoterodine
Other interactions of Rimabotulinumtoxinb
- Amikacin + Rimabotulinumtoxinb Moderate
- Amitriptyline + Rimabotulinumtoxinb Moderate
- Atracurium + Rimabotulinumtoxinb Moderate
- Atropine + Rimabotulinumtoxinb Moderate
- Baclofen + Rimabotulinumtoxinb Moderate
- Benztropine + Rimabotulinumtoxinb Moderate
Frequently asked questions
Can I take Fesoterodine with Rimabotulinumtoxinb?
MediHelp rates the interaction as moderate. Fesoterodine and Rimabotulinumtoxinb can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Anticholinergic drugs may potentiate botulinum toxin effects, increasing neuromuscular weakness and systemic anticholinergic effects. Rimabotulinumtoxin B in particular is associated with dry mouth, which may be compounded.
How serious is the interaction between Fesoterodine and Rimabotulinumtoxinb?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for generalized weakness, dysphagia, respiratory difficulty and marked dry mouth after injection. Consider holding fesoterodine if these develop.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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