Drug interactions
Fesoterodine + Ziprasidone
Severity: Minor
Fesoterodine and Ziprasidone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ziprasidone has weak anticholinergic activity, so additive antimuscarinic effects are possible but usually modest. No established pharmacokinetic interaction exists.
What this interaction means in plain words
Fesoterodine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fesoterodine belongs to Genitourinary; Ziprasidone belongs to Central Nervous System.
Why it happens
Possible additive antimuscarinic effects; mechanism not firmly established.
What to do
Monitor for constipation, dry mouth and urinary retention, particularly in elderly patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fesoterodine
Other interactions of Ziprasidone
- Amiodarone + Ziprasidone Contraindicated
- Amitriptyline + Ziprasidone Contraindicated
- Arsenic trioxide + Ziprasidone Contraindicated
- Bedaquiline + Ziprasidone Contraindicated
- Chloroquine + Ziprasidone Contraindicated
- Citalopram + Ziprasidone Contraindicated
Frequently asked questions
Can I take Fesoterodine with Ziprasidone?
MediHelp rates the interaction as minor. Fesoterodine and Ziprasidone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ziprasidone has weak anticholinergic activity, so additive antimuscarinic effects are possible but usually modest. No established pharmacokinetic interaction exists.
How serious is the interaction between Fesoterodine and Ziprasidone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for constipation, dry mouth and urinary retention, particularly in elderly patients.
What other medicines interact with Fesoterodine?
MediHelp also lists interactions of Fesoterodine with, for example, Bethanechol, Clozapine, Levoketoconazole. The full list is on the Fesoterodine page.
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