Drug interactions
Fingolimod + Formoterol-mometasone
Severity: Moderate
Fingolimod and Formoterol-mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod causes bradycardia and can prolong QT, while formoterol can affect QTc and raise heart rate. Combined use may add to arrhythmia risk, especially at treatment initiation.
What this interaction means in plain words
Fingolimod and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Formoterol-mometasone belongs to Respiratory.
Why it happens
Additive QT prolongation, with fingolimod-induced bradycardia increasing proarrhythmic susceptibility.
What to do
Obtain an ECG and correct electrolytes before starting fingolimod in patients on formoterol, and monitor heart rate after the first dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Formoterol-mometasone?
MediHelp rates the interaction as moderate. Fingolimod and Formoterol-mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod causes bradycardia and can prolong QT, while formoterol can affect QTc and raise heart rate. Combined use may add to arrhythmia risk, especially at treatment initiation.
How serious is the interaction between Fingolimod and Formoterol-mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain an ECG and correct electrolytes before starting fingolimod in patients on formoterol, and monitor heart rate after the first dose.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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