Drug interactions
Fingolimod + Ipratropium-salbutamol
Severity: Moderate
Fingolimod and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fingolimod slows heart rate and can prolong the QT interval, particularly at treatment initiation. Salbutamol is a beta-agonist that can cause tachycardia, hypokalemia and arrhythmia, especially at high doses. Together they may add to the risk of rhythm disturbances.
What this interaction means in plain words
Fingolimod and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Additive effects on cardiac conduction and repolarization, with salbutamol-induced hypokalemia increasing arrhythmia susceptibility.
What to do
Monitor ECG and heart rate, particularly during fingolimod initiation, and check potassium if salbutamol is used frequently or at high doses. Avoid excessive salbutamol use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Fingolimod and Ipratropium-salbutamol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ipratropium-salbutamol
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Fingolimod and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fingolimod slows heart rate and can prolong the QT interval, particularly at treatment initiation. Salbutamol is a beta-agonist that can cause tachycardia, hypokalemia and arrhythmia, especially at high doses. Together they may add to the risk of rhythm disturbances.
How serious is the interaction between Fingolimod and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and heart rate, particularly during fingolimod initiation, and check potassium if salbutamol is used frequently or at high doses. Avoid excessive salbutamol use.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
