Drug interactions
Fingolimod + Prednisone
Severity: Moderate
Fingolimod and Prednisone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Prednisone and fingolimod both suppress immune function, so combined use may raise the risk of infection. The risk is highest with higher or prolonged corticosteroid doses.
What this interaction means in plain words
Fingolimod and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fingolimod belongs to Central Nervous System; Prednisone belongs to Endocrine.
Why it happens
Additive immunosuppression from corticosteroid effects and fingolimod-induced lymphocyte sequestration.
What to do
Monitor for signs of infection and check lymphocyte counts. Use the lowest effective corticosteroid dose and duration.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Prednisone
- Bcg vaccine live + Prednisone Contraindicated
- Measles vaccine + Prednisone Contraindicated
- Mifepristone + Prednisone Contraindicated
- Prednisone + Radium-223 dichloride Contraindicated
- Prednisone + Smallpox vaccine live Contraindicated
- Adenovirus types 4 and 7 live + Prednisone Major
Other interactions of Fingolimod
- Adenovirus types 4 and 7 live + Fingolimod Contraindicated
- Bcg vaccine live + Fingolimod Contraindicated
- Fingolimod + Pimozide Contraindicated
- Fingolimod + Ponesimod Contraindicated
- Fingolimod + Quinidine Contraindicated
- Fingolimod + Siponimod Contraindicated
Frequently asked questions
Can I take Fingolimod with Prednisone?
MediHelp rates the interaction as moderate. Fingolimod and Prednisone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Prednisone and fingolimod both suppress immune function, so combined use may raise the risk of infection. The risk is highest with higher or prolonged corticosteroid doses.
How serious is the interaction between Fingolimod and Prednisone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of infection and check lymphocyte counts. Use the lowest effective corticosteroid dose and duration.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Mifepristone. The full list is on the Prednisone page.
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