Drug interactions
Fish oil + Ticagrelor
Severity: Minor
Fish oil and Ticagrelor: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose omega-3 fatty acids may have a mild antiplatelet effect. With ticagrelor, a small increase in bleeding tendency is possible.
What this interaction means in plain words
Fish oil and Ticagrelor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fish oil belongs to Gastrointestinal Tract; Ticagrelor belongs to Cardiovascular.
Why it happens
Omega-3 fatty acids may mildly impair platelet aggregation, adding to P2Y12 inhibition.
What to do
No dose change is usually needed; counsel patients to report unusual bleeding or bruising, especially at high fish oil doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticagrelor
- Itraconazole + Ticagrelor Contraindicated
- Ketoconazole + Ticagrelor Contraindicated
- Levoketoconazole + Ticagrelor Contraindicated
- Abciximab + Ticagrelor Major
- Abrocitinib + Ticagrelor Major
- Acalabrutinib + Ticagrelor Major
Other interactions of Fish oil
- Antithrombin alfa + Fish oil Moderate
- Antithrombin iii + Fish oil Moderate
- Aspirin / citric acid / sodium bicarbonate + Fish oil Moderate
- Aspirin + Fish oil Moderate
- Betrixaban + Fish oil Moderate
- Bivalirudin + Fish oil Moderate
Frequently asked questions
Can I take Fish oil with Ticagrelor?
MediHelp rates the interaction as minor. Fish oil and Ticagrelor have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose omega-3 fatty acids may have a mild antiplatelet effect. With ticagrelor, a small increase in bleeding tendency is possible.
How serious is the interaction between Fish oil and Ticagrelor?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; counsel patients to report unusual bleeding or bruising, especially at high fish oil doses.
What other medicines interact with Ticagrelor?
MediHelp also lists interactions of Ticagrelor with, for example, Itraconazole, Ketoconazole, Levoketoconazole. The full list is on the Ticagrelor page.
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