Drug interactions
Flavoxate + Oxybutynin
Severity: Moderate
Flavoxate and Oxybutynin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Flavoxate has antispasmodic and mild anticholinergic properties, so combined use with oxybutynin may add to dry mouth, blurred vision, drowsiness and urinary retention. Evidence for a significant interaction is limited.
What this interaction means in plain words
Flavoxate and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Flavoxate belongs to Genitourinary; Oxybutynin belongs to Genitourinary.
Why it happens
Additive antimuscarinic and smooth muscle relaxant effects.
What to do
Monitor for anticholinergic adverse effects and urinary retention, and avoid duplicate bladder antispasmodic therapy unless clearly needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Oxybutynin
Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Frequently asked questions
Can I take Flavoxate with Oxybutynin?
MediHelp rates the interaction as moderate. Flavoxate and Oxybutynin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flavoxate has antispasmodic and mild anticholinergic properties, so combined use with oxybutynin may add to dry mouth, blurred vision, drowsiness and urinary retention. Evidence for a significant interaction is limited.
How serious is the interaction between Flavoxate and Oxybutynin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects and urinary retention, and avoid duplicate bladder antispasmodic therapy unless clearly needed.
What other medicines interact with Oxybutynin?
MediHelp also lists interactions of Oxybutynin with, for example, Bethanechol, Clozapine, Potassium chloride. The full list is on the Oxybutynin page.
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