Drug interactions
Flavoxate + Scopolamine
Severity: Moderate
Flavoxate and Scopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Flavoxate has antimuscarinic and smooth muscle relaxant actions, so combined use with scopolamine can intensify anticholinergic effects such as dry mouth, blurred vision, drowsiness, confusion and urinary retention.
What this interaction means in plain words
Flavoxate and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Flavoxate belongs to Genitourinary; Scopolamine belongs to Respiratory.
Why it happens
Additive muscarinic receptor antagonism.
What to do
Monitor for anticholinergic adverse effects and avoid use in patients with glaucoma or obstructive uropathy. Reduce or stop one agent if toxicity occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Scopolamine
Other interactions of Flavoxate
- Clozapine + Flavoxate Major
- Abobotulinumtoxina + Flavoxate Moderate
- Aclidinium + Flavoxate Moderate
- Amantadine + Flavoxate Moderate
- Amitriptyline + Flavoxate Moderate
- Amoxapine + Flavoxate Moderate
Frequently asked questions
Can I take Flavoxate with Scopolamine?
MediHelp rates the interaction as moderate. Flavoxate and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flavoxate has antimuscarinic and smooth muscle relaxant actions, so combined use with scopolamine can intensify anticholinergic effects such as dry mouth, blurred vision, drowsiness, confusion and urinary retention.
How serious is the interaction between Flavoxate and Scopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects and avoid use in patients with glaucoma or obstructive uropathy. Reduce or stop one agent if toxicity occurs.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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