Drug interactions
Fleroxacin + Isotretinoin
Severity: Minor
Fleroxacin and Isotretinoin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both isotretinoin and fluoroquinolones such as fleroxacin can cause photosensitivity. Used together, patients may sunburn or develop phototoxic skin reactions more readily.
What this interaction means in plain words
Fleroxacin and Isotretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive photosensitizing effects of the two drugs.
What to do
Advise strict sun avoidance, protective clothing and broad-spectrum sunscreen; stop fleroxacin if a phototoxic reaction occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Isotretinoin
- Demeclocycline + Isotretinoin Contraindicated
- Isotretinoin + Minocycline Contraindicated
- Isotretinoin + Oxytetracycline Contraindicated
- Isotretinoin + Palovarotene Contraindicated
- Aminolevulinic acid + Isotretinoin Major
- Doxycycline + Isotretinoin Major
Frequently asked questions
Can I take Fleroxacin with Isotretinoin?
MediHelp rates the interaction as minor. Fleroxacin and Isotretinoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both isotretinoin and fluoroquinolones such as fleroxacin can cause photosensitivity. Used together, patients may sunburn or develop phototoxic skin reactions more readily.
How serious is the interaction between Fleroxacin and Isotretinoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise strict sun avoidance, protective clothing and broad-spectrum sunscreen; stop fleroxacin if a phototoxic reaction occurs.
What other medicines interact with Isotretinoin?
MediHelp also lists interactions of Isotretinoin with, for example, Demeclocycline, Minocycline, Oxytetracycline. The full list is on the Isotretinoin page.
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