Drug interactions
Flibanserin + Ginko biloba
Severity: Moderate
Flibanserin and Ginko biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Flibanserin is metabolised mainly by CYP3A4, and ginkgo may weakly inhibit this enzyme, possibly raising flibanserin levels. Higher exposure could increase hypotension, syncope and sedation, particularly with alcohol or other CYP3A4 inhibitors.
What this interaction means in plain words
Flibanserin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Flibanserin belongs to Genitourinary; Ginko biloba belongs to Gastrointestinal Tract.
Why it happens
Possible weak CYP3A4 inhibition by ginkgo, reducing flibanserin clearance; evidence for ginkgo effect is inconsistent.
What to do
Counsel patients to avoid ginkgo products, particularly if other CYP3A4 inhibitors are used, and to report dizziness or fainting.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Flibanserin
- Atazanavir + Flibanserin Contraindicated
- Ceritinib + Flibanserin Contraindicated
- Clarithromycin + Flibanserin Contraindicated
- Cobicistat + Flibanserin Contraindicated
- Conivaptan + Flibanserin Contraindicated
- Crizotinib + Flibanserin Contraindicated
Frequently asked questions
Can I take Flibanserin with Ginko biloba?
MediHelp rates the interaction as moderate. Flibanserin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Flibanserin is metabolised mainly by CYP3A4, and ginkgo may weakly inhibit this enzyme, possibly raising flibanserin levels. Higher exposure could increase hypotension, syncope and sedation, particularly with alcohol or other CYP3A4 inhibitors.
How serious is the interaction between Flibanserin and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid ginkgo products, particularly if other CYP3A4 inhibitors are used, and to report dizziness or fainting.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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