Drug interactions
Fluoxetine + Foscarnet
Severity: Moderate
Fluoxetine and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both can prolong the QT interval, and foscarnet-related hypocalcemia or hypomagnesemia raises the risk. The combination may predispose to torsades de pointes.
What this interaction means in plain words
Fluoxetine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fluoxetine belongs to Central Nervous System; Foscarnet belongs to Anti Virals.
Why it happens
Additive QT prolongation with electrolyte disturbance.
What to do
Monitor ECG in patients with additional QT risk factors and correct electrolytes during foscarnet therapy. Consider an alternative if QTc becomes prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Fluoxetine
- Fluoxetine + Isocarboxazid Contraindicated
- Fluoxetine + Mavacamten Contraindicated
- Fluoxetine + Methylene blue Contraindicated
- Fluoxetine + Phenelzine Contraindicated
- Fluoxetine + Pimozide Contraindicated
- Fluoxetine + Rasagiline Contraindicated
Frequently asked questions
Can I take Fluoxetine with Foscarnet?
MediHelp rates the interaction as moderate. Fluoxetine and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both can prolong the QT interval, and foscarnet-related hypocalcemia or hypomagnesemia raises the risk. The combination may predispose to torsades de pointes.
How serious is the interaction between Fluoxetine and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG in patients with additional QT risk factors and correct electrolytes during foscarnet therapy. Consider an alternative if QTc becomes prolonged.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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