Drug interactions
Fluphenazine + Levosalbutamol
Severity: Minor
Fluphenazine and Levosalbutamol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fluphenazine is a phenothiazine that can prolong the QT interval, and high-dose beta-2 agonists may add to this effect, especially with hypokalemia. Fluphenazine's sedative effect is not meaningfully offset by levosalbutamol.
What this interaction means in plain words
Fluphenazine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluphenazine belongs to Central Nervous System; Levosalbutamol belongs to Respiratory.
Why it happens
Possible additive effect on cardiac repolarization; beta-2 agonist hypokalemia may increase susceptibility.
What to do
No routine action is needed at usual doses. Check potassium and consider an ECG if high doses of levosalbutamol are given or other QT risk factors are present.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Levosalbutamol
Other interactions of Fluphenazine
- Arsenic trioxide + Fluphenazine Contraindicated
- Dofetilide + Fluphenazine Contraindicated
- Fluphenazine + Ibutilide Contraindicated
- Fluphenazine + Pimozide Contraindicated
- Adagrasib + Fluphenazine Major
- Alfentanil + Fluphenazine Major
Frequently asked questions
Can I take Fluphenazine with Levosalbutamol?
MediHelp rates the interaction as minor. Fluphenazine and Levosalbutamol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fluphenazine is a phenothiazine that can prolong the QT interval, and high-dose beta-2 agonists may add to this effect, especially with hypokalemia. Fluphenazine's sedative effect is not meaningfully offset by levosalbutamol.
How serious is the interaction between Fluphenazine and Levosalbutamol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed at usual doses. Check potassium and consider an ECG if high doses of levosalbutamol are given or other QT risk factors are present.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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