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Drug interactions

Fluphenazine + Motherwort

Severity: Minor

Fluphenazine and Motherwort: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Motherwort has mild sedative properties traditionally, which may add to the sedation caused by fluphenazine. Clinical data are very limited.

What this interaction means in plain words

Fluphenazine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive central nervous system depression; not well characterized.

What to do

Counsel the patient about additive drowsiness and advise avoiding driving if sedation occurs. Consider stopping the herbal product if excessive sedation develops.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Fluphenazine with Motherwort?

MediHelp rates the interaction as minor. Fluphenazine and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has mild sedative properties traditionally, which may add to the sedation caused by fluphenazine. Clinical data are very limited.

How serious is the interaction between Fluphenazine and Motherwort?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about additive drowsiness and advise avoiding driving if sedation occurs. Consider stopping the herbal product if excessive sedation develops.

What other medicines interact with Fluphenazine?

MediHelp also lists interactions of Fluphenazine with, for example, Arsenic trioxide, Dofetilide, Ibutilide. The full list is on the Fluphenazine page.

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