Drug interactions
Flurbiprofen + Terbinafine
Severity: Minor
Flurbiprofen and Terbinafine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Terbinafine is not a clinically important CYP2C9 inhibitor, so a meaningful rise in flurbiprofen exposure is not expected. No relevant interaction is established.
What this interaction means in plain words
Flurbiprofen and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Flurbiprofen belongs to Musculoskeletal; Terbinafine belongs to Anti Fungals.
Why it happens
Terbinafine mainly inhibits CYP2D6; effects on CYP2C9 are not established.
What to do
No dose adjustment is needed; monitor for usual NSAID adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Other interactions of Terbinafine
- Terbinafine + Thioridazine Contraindicated
- Desipramine + Terbinafine Major
- Eliglustat + Terbinafine Major
- Flecainide + Terbinafine Major
- Imipramine + Terbinafine Major
- Maprotiline + Terbinafine Major
Frequently asked questions
Can I take Flurbiprofen with Terbinafine?
MediHelp rates the interaction as minor. Flurbiprofen and Terbinafine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Terbinafine is not a clinically important CYP2C9 inhibitor, so a meaningful rise in flurbiprofen exposure is not expected. No relevant interaction is established.
How serious is the interaction between Flurbiprofen and Terbinafine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor for usual NSAID adverse effects.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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