Drug interactions
Fluvoxamine + Lonapegsomatropin
Severity: Minor
Fluvoxamine and Lonapegsomatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may increase CYP-mediated clearance, so it could slightly lower levels of sensitive CYP substrates. Fluvoxamine is a CYP1A2 substrate, but a clinically meaningful change has not been shown.
What this interaction means in plain words
Fluvoxamine and Lonapegsomatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvoxamine belongs to Central Nervous System; Lonapegsomatropin belongs to Endocrine.
Why it happens
Possible growth hormone induction of CYP activity; not firmly established.
What to do
No dose adjustment is needed; monitor antidepressant response if lonapegsomatropin is started or stopped.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Other interactions of Lonapegsomatropin
Frequently asked questions
Can I take Fluvoxamine with Lonapegsomatropin?
MediHelp rates the interaction as minor. Fluvoxamine and Lonapegsomatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may increase CYP-mediated clearance, so it could slightly lower levels of sensitive CYP substrates. Fluvoxamine is a CYP1A2 substrate, but a clinically meaningful change has not been shown.
How serious is the interaction between Fluvoxamine and Lonapegsomatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor antidepressant response if lonapegsomatropin is started or stopped.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Fezolinetant. The full list is on the Fluvoxamine page.
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