Drug interactions
Fluvoxamine + Somatropin
Severity: Minor
Fluvoxamine and Somatropin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Growth hormone may induce certain CYP enzymes, including CYP1A2, which could slightly lower fluvoxamine concentrations. Clinical evidence is limited and the effect is likely small.
What this interaction means in plain words
Fluvoxamine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fluvoxamine belongs to Central Nervous System; Somatropin belongs to Endocrine.
Why it happens
Possible induction of CYP-mediated metabolism by somatropin.
What to do
No routine change is needed. Monitor antidepressant response when somatropin is started or its dose changed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Other interactions of Somatropin
- Acarbose + Somatropin Moderate
- Albiglutide + Somatropin Moderate
- Alogliptin-metformin + Somatropin Moderate
- Alogliptin-pioglitazone + Somatropin Moderate
- Alogliptin + Somatropin Moderate
- Betamethasone + Somatropin Moderate
Frequently asked questions
Can I take Fluvoxamine with Somatropin?
MediHelp rates the interaction as minor. Fluvoxamine and Somatropin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Growth hormone may induce certain CYP enzymes, including CYP1A2, which could slightly lower fluvoxamine concentrations. Clinical evidence is limited and the effect is likely small.
How serious is the interaction between Fluvoxamine and Somatropin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor antidepressant response when somatropin is started or its dose changed.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Fezolinetant. The full list is on the Fluvoxamine page.
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