Drug interactions
Fluvoxamine + Valerian
Severity: Minor
Fluvoxamine and Valerian: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valerian has sedative properties and may add to the drowsiness caused by fluvoxamine. Impaired alertness and psychomotor performance may result.
What this interaction means in plain words
Fluvoxamine and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive central nervous system depressant effects via GABAergic activity.
What to do
Advise patients to watch for excessive drowsiness and avoid driving if affected. Stop valerian if sedation becomes troublesome.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fluvoxamine
- Agomelatine + Fluvoxamine Contraindicated
- Alosetron + Fluvoxamine Contraindicated
- Fezolinetant + Fluvoxamine Contraindicated
- Fluvoxamine + Isocarboxazid Contraindicated
- Fluvoxamine + Mavacamten Contraindicated
- Fluvoxamine + Methylene blue Contraindicated
Frequently asked questions
Can I take Fluvoxamine with Valerian?
MediHelp rates the interaction as minor. Fluvoxamine and Valerian have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Valerian has sedative properties and may add to the drowsiness caused by fluvoxamine. Impaired alertness and psychomotor performance may result.
How serious is the interaction between Fluvoxamine and Valerian?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excessive drowsiness and avoid driving if affected. Stop valerian if sedation becomes troublesome.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Fezolinetant. The full list is on the Fluvoxamine page.
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