Drug interactions
Fondaparinux + Forskolin
Severity: Moderate
Fondaparinux and Forskolin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin raises intracellular cAMP and can inhibit platelet aggregation. This may theoretically add to the bleeding risk of fondaparinux.
What this interaction means in plain words
Fondaparinux and Forskolin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Adenylyl cyclase activation increases platelet cAMP and inhibits aggregation, adding to factor Xa inhibition.
What to do
Avoid forskolin supplements during fondaparinux therapy, and monitor for bleeding if used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Fondaparinux with Forskolin?
MediHelp rates the interaction as moderate. Fondaparinux and Forskolin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Forskolin raises intracellular cAMP and can inhibit platelet aggregation. This may theoretically add to the bleeding risk of fondaparinux.
How serious is the interaction between Fondaparinux and Forskolin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid forskolin supplements during fondaparinux therapy, and monitor for bleeding if used.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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