Drug interactions
Fondaparinux + Ginko biloba
Severity: Moderate
Fondaparinux and Ginko biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo biloba may impair platelet function and add to the bleeding risk of fondaparinux. Evidence is limited and mainly theoretical.
What this interaction means in plain words
Fondaparinux and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fondaparinux belongs to Cardiovascular; Ginko biloba belongs to Gastrointestinal Tract.
Why it happens
Ginkgo's platelet-activating factor antagonism adds antiplatelet effects to fondaparinux's factor Xa inhibition.
What to do
Advise stopping ginkgo during fondaparinux therapy. Monitor for bleeding signs and hemoglobin.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Fondaparinux with Ginko biloba?
MediHelp rates the interaction as moderate. Fondaparinux and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may impair platelet function and add to the bleeding risk of fondaparinux. Evidence is limited and mainly theoretical.
How serious is the interaction between Fondaparinux and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise stopping ginkgo during fondaparinux therapy. Monitor for bleeding signs and hemoglobin.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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