Drug interactions
Fondaparinux + Pau d'arco
Severity: Minor
Fondaparinux and Pau d'arco: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pau d'arco contains naphthoquinones that may interfere with vitamin K and coagulation, so an added bleeding tendency has been suggested. Evidence is theoretical.
What this interaction means in plain words
Fondaparinux and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible anticoagulant-like activity of naphthoquinones; not well established.
What to do
Advise avoiding pau d'arco while on fondaparinux. Monitor for bleeding if it is used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Frequently asked questions
Can I take Fondaparinux with Pau d'arco?
MediHelp rates the interaction as minor. Fondaparinux and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco contains naphthoquinones that may interfere with vitamin K and coagulation, so an added bleeding tendency has been suggested. Evidence is theoretical.
How serious is the interaction between Fondaparinux and Pau d'arco?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding pau d'arco while on fondaparinux. Monitor for bleeding if it is used.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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