Drug interactions
Formoterol + Osilodrostat
Severity: Moderate
Formoterol and Osilodrostat: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Osilodrostat can prolong the QT interval, and formoterol may add to this effect. Hypokalemia, which either drug can cause or worsen, further raises the arrhythmia risk.
What this interaction means in plain words
Formoterol and Osilodrostat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Osilodrostat belongs to Endocrine.
Why it happens
Additive QTc prolongation.
What to do
Obtain a baseline ECG and monitor QTc, potassium and magnesium, correcting abnormalities before and during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Osilodrostat
Frequently asked questions
Can I take Formoterol with Osilodrostat?
MediHelp rates the interaction as moderate. Formoterol and Osilodrostat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Osilodrostat can prolong the QT interval, and formoterol may add to this effect. Hypokalemia, which either drug can cause or worsen, further raises the arrhythmia risk.
How serious is the interaction between Formoterol and Osilodrostat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and monitor QTc, potassium and magnesium, correcting abnormalities before and during therapy.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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