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Drug interactions

Formoterol + Oxaliplatin

Severity: Moderate

Formoterol and Oxaliplatin: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Oxaliplatin has been associated with QT prolongation and torsades de pointes, and formoterol can also affect cardiac repolarization and lower potassium. Using them together may increase the risk of QT-related arrhythmias, especially with electrolyte disturbances from chemotherapy.

What this interaction means in plain words

Formoterol and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Formoterol belongs to Respiratory; Oxaliplatin belongs to Oncology.

Evidence level: Low

Why it happens

Additive QT prolongation, aggravated by hypokalemia or hypomagnesemia.

What to do

Check baseline ECG, potassium and magnesium, and correct abnormalities before and during therapy. Monitor QTc periodically in patients with additional risk factors.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Formoterol with Oxaliplatin?

MediHelp rates the interaction as moderate. Formoterol and Oxaliplatin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oxaliplatin has been associated with QT prolongation and torsades de pointes, and formoterol can also affect cardiac repolarization and lower potassium. Using them together may increase the risk of QT-related arrhythmias, especially with electrolyte disturbances from chemotherapy.

How serious is the interaction between Formoterol and Oxaliplatin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG, potassium and magnesium, and correct abnormalities before and during therapy. Monitor QTc periodically in patients with additional risk factors.

What other medicines interact with Formoterol?

MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.

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