Drug interactions
Formoterol + Voriconazole
Severity: Moderate
Formoterol and Voriconazole: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voriconazole is associated with QT prolongation and torsades de pointes, and formoterol may add QTc effects and lower potassium. The combination may raise arrhythmia risk, especially with hypokalemia or cardiac disease.
What this interaction means in plain words
Formoterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol belongs to Respiratory; Voriconazole belongs to Anti Fungals.
Why it happens
Additive QT prolongation with beta2-agonist-induced hypokalemia.
What to do
Correct potassium and magnesium before starting, obtain a baseline ECG in at-risk patients, and monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Voriconazole
- Avanafil + Voriconazole Contraindicated
- Butabarbital + Voriconazole Contraindicated
- Carbamazepine + Voriconazole Contraindicated
- Conivaptan + Voriconazole Contraindicated
- Dihydroergotamine intranasal + Voriconazole Contraindicated
- Dihydroergotamine + Voriconazole Contraindicated
Frequently asked questions
Can I take Formoterol with Voriconazole?
MediHelp rates the interaction as moderate. Formoterol and Voriconazole can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Voriconazole is associated with QT prolongation and torsades de pointes, and formoterol may add QTc effects and lower potassium. The combination may raise arrhythmia risk, especially with hypokalemia or cardiac disease.
How serious is the interaction between Formoterol and Voriconazole?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct potassium and magnesium before starting, obtain a baseline ECG in at-risk patients, and monitor for palpitations or syncope.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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