Drug interactions
Formoterol-mometasone + Imipramine
Severity: Moderate
Formoterol-mometasone and Imipramine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Imipramine can prolong QT and may potentiate cardiovascular effects of beta-agonists. Formoterol hypokalemia adds to the risk of arrhythmia.
What this interaction means in plain words
Formoterol-mometasone and Imipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Imipramine belongs to Central Nervous System.
Why it happens
Additive QT prolongation and adrenergic potentiation from norepinephrine reuptake inhibition.
What to do
Monitor heart rate, ECG and potassium, particularly in patients with heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Imipramine
- Dronedarone + Imipramine Contraindicated
- Imipramine + Isocarboxazid Contraindicated
- Imipramine + Phenelzine Contraindicated
- Imipramine + Pimozide Contraindicated
- Imipramine + Rasagiline Contraindicated
- Imipramine + Safinamide Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Imipramine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Imipramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Imipramine can prolong QT and may potentiate cardiovascular effects of beta-agonists. Formoterol hypokalemia adds to the risk of arrhythmia.
How serious is the interaction between Formoterol-mometasone and Imipramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, ECG and potassium, particularly in patients with heart disease.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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