Drug interactions
Formoterol-mometasone + Ivosidenib
Severity: Moderate
Formoterol-mometasone and Ivosidenib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ivosidenib can prolong the QT interval. Formoterol may add to this effect and lower potassium, which raises the chance of serious ventricular arrhythmia.
What this interaction means in plain words
Formoterol-mometasone and Ivosidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Ivosidenib belongs to Oncology.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia contributing.
What to do
Monitor ECG and electrolytes, correcting potassium and magnesium. Consider an alternative bronchodilator, or reduce the ivosidenib dose per labeling if QTc prolongs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Ivosidenib
- Alfuzosin + Ivosidenib Major
- Amiodarone + Ivosidenib Major
- Amisulpride + Ivosidenib Major
- Amitriptyline + Ivosidenib Major
- Amobarbital + Ivosidenib Major
- Anagrelide + Ivosidenib Major
Frequently asked questions
Can I take Formoterol-mometasone with Ivosidenib?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Ivosidenib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ivosidenib can prolong the QT interval. Formoterol may add to this effect and lower potassium, which raises the chance of serious ventricular arrhythmia.
How serious is the interaction between Formoterol-mometasone and Ivosidenib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes, correcting potassium and magnesium. Consider an alternative bronchodilator, or reduce the ivosidenib dose per labeling if QTc prolongs.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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