Drug interactions
Formoterol-mometasone + Lefamulin
Severity: Moderate
Formoterol-mometasone and Lefamulin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lefamulin can prolong the QT interval, particularly with intravenous use. Formoterol may add to QT effects and lower potassium, increasing arrhythmia risk.
What this interaction means in plain words
Formoterol-mometasone and Lefamulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Lefamulin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, with beta-2 agonist induced hypokalemia contributing.
What to do
Check baseline ECG and correct potassium and magnesium. Monitor the ECG during therapy in patients with other QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Lefamulin
- Lefamulin + Methadone Contraindicated
- Lefamulin + Pimavanserin Contraindicated
- Lefamulin + Pimozide Contraindicated
- Lefamulin + Quinidine Contraindicated
- Alfuzosin + Lefamulin Major
- Amiodarone + Lefamulin Major
Frequently asked questions
Can I take Formoterol-mometasone with Lefamulin?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Lefamulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lefamulin can prolong the QT interval, particularly with intravenous use. Formoterol may add to QT effects and lower potassium, increasing arrhythmia risk.
How serious is the interaction between Formoterol-mometasone and Lefamulin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and correct potassium and magnesium. Monitor the ECG during therapy in patients with other QT risk factors.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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