Drug interactions
Formoterol-mometasone + Nortriptyline
Severity: Moderate
Formoterol-mometasone and Nortriptyline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic antidepressants can prolong the QT interval and may potentiate the cardiovascular effects of beta2-agonists, including tachycardia and arrhythmia. Formoterol labeling advises caution with tricyclics for this reason.
What this interaction means in plain words
Formoterol-mometasone and Nortriptyline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Nortriptyline belongs to Central Nervous System.
Why it happens
Additive QT prolongation and potentiation of adrenergic cardiovascular effects.
What to do
Monitor ECG and heart rate, particularly at the start of therapy or with dose increases. Correct hypokalemia and avoid exceeding recommended formoterol doses.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Nortriptyline
- Disopyramide + Nortriptyline Contraindicated
- Dofetilide + Nortriptyline Contraindicated
- Dronedarone + Nortriptyline Contraindicated
- Ibutilide + Nortriptyline Contraindicated
- Isocarboxazid + Nortriptyline Contraindicated
- Methylene blue + Nortriptyline Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Nortriptyline?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Nortriptyline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tricyclic antidepressants can prolong the QT interval and may potentiate the cardiovascular effects of beta2-agonists, including tachycardia and arrhythmia. Formoterol labeling advises caution with tricyclics for this reason.
How serious is the interaction between Formoterol-mometasone and Nortriptyline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and heart rate, particularly at the start of therapy or with dose increases. Correct hypokalemia and avoid exceeding recommended formoterol doses.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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