Drug interactions
Formoterol-mometasone + Ofloxacin
Severity: Moderate
Formoterol-mometasone and Ofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ofloxacin and formoterol can both prolong the QTc interval, so combined use may raise the risk of ventricular arrhythmia, especially with hypokalemia. Fluoroquinolones together with corticosteroids also increase tendinopathy risk, although this is small with inhaled mometasone.
What this interaction means in plain words
Formoterol-mometasone and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Ofloxacin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, plus additive tendon toxicity of fluoroquinolones and corticosteroids.
What to do
Consider an ECG and correct potassium and magnesium in patients with QT risk factors. Advise patients to stop ofloxacin and seek care if tendon pain develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Ofloxacin
- Ofloxacin + Thioridazine Contraindicated
- Adagrasib + Ofloxacin Major
- Amiodarone + Ofloxacin Major
- Amisulpride + Ofloxacin Major
- Anagrelide + Ofloxacin Major
- Arsenic trioxide + Ofloxacin Major
Frequently asked questions
Can I take Formoterol-mometasone with Ofloxacin?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Ofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ofloxacin and formoterol can both prolong the QTc interval, so combined use may raise the risk of ventricular arrhythmia, especially with hypokalemia. Fluoroquinolones together with corticosteroids also increase tendinopathy risk, although this is small with inhaled mometasone.
How serious is the interaction between Formoterol-mometasone and Ofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider an ECG and correct potassium and magnesium in patients with QT risk factors. Advise patients to stop ofloxacin and seek care if tendon pain develops.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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