Drug interactions
Formoterol-mometasone + Quinine
Severity: Moderate
Formoterol-mometasone and Quinine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quinine prolongs the QT interval and can cause serious arrhythmias, and formoterol may add to repolarization effects and lower potassium. Together they may increase the risk of torsades de pointes.
What this interaction means in plain words
Formoterol-mometasone and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Quinine belongs to Anti Parasitic.
Why it happens
Additive QTc prolongation, with beta-2-agonist-induced hypokalemia potentially amplifying risk.
What to do
Obtain a baseline ECG and correct potassium and magnesium before starting quinine. Monitor for palpitations or syncope and consider alternatives in patients with QT risk factors.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Quinine
- Arsenic trioxide + Quinine Contraindicated
- Dofetilide + Quinine Contraindicated
- Dronedarone + Quinine Contraindicated
- Ibutilide + Quinine Contraindicated
- Mefloquine + Quinine Contraindicated
- Nilotinib + Quinine Contraindicated
Frequently asked questions
Can I take Formoterol-mometasone with Quinine?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Quinine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quinine prolongs the QT interval and can cause serious arrhythmias, and formoterol may add to repolarization effects and lower potassium. Together they may increase the risk of torsades de pointes.
How serious is the interaction between Formoterol-mometasone and Quinine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct potassium and magnesium before starting quinine. Monitor for palpitations or syncope and consider alternatives in patients with QT risk factors.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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