Drug interactions
Formoterol-mometasone + Selpercatinib
Severity: Moderate
Formoterol-mometasone and Selpercatinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both formoterol and selpercatinib can prolong the QT interval. Used together they may increase the risk of torsades de pointes, especially with electrolyte disturbance or underlying heart disease.
What this interaction means in plain words
Formoterol-mometasone and Selpercatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Formoterol-mometasone belongs to Respiratory; Selpercatinib belongs to Oncology.
Why it happens
Additive QT interval prolongation.
What to do
Monitor ECG and correct potassium and magnesium before and during therapy. Reassess the need for formoterol if the QTc becomes prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol-mometasone
Other interactions of Selpercatinib
Frequently asked questions
Can I take Formoterol-mometasone with Selpercatinib?
MediHelp rates the interaction as moderate. Formoterol-mometasone and Selpercatinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both formoterol and selpercatinib can prolong the QT interval. Used together they may increase the risk of torsades de pointes, especially with electrolyte disturbance or underlying heart disease.
How serious is the interaction between Formoterol-mometasone and Selpercatinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and correct potassium and magnesium before and during therapy. Reassess the need for formoterol if the QTc becomes prolonged.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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